Advance 66™
A foliar biostimulant with chelated zinc and Nutriphite® potassium-phosphite technology designed to maximise nutrient-use efficiency, enhance root development, increase nutrient uptake and nitrogen utilisation, and support stronger crop establishment, growth, yield and quality.
Verdesian links Advance 66™ with increased nitrate reductase and cis-zeatin and reports a 30% increase in root mass in cereals in the cited technology studies, creating greater potential contact between roots, soil water and available nutrients.
Current European manufacturer guidance lists 1–2 L/ha per application, subject to the approved local label. Manufacturer biochemical and root-response figures are reported responses and are not guaranteed under every crop or environment.
Linking root development, zinc nutrition and nitrogen metabolism
Advance 66™ combines two complementary crop-nutrition concepts: micronutrient nutrition from chelated zinc and Verdesian's Nutriphite® potassium-phosphite technology.
Current manufacturer positioning focuses on improving the plant's ability to acquire and utilise available nutrients rather than simply adding a large quantity of fertiliser.
The product is designed for foliar application and is positioned to support crop establishment, root development, nitrogen utilisation, growth, yield and quality.
Current European profile
Chelated zinc + Nutriphite®
Chelated zinc
Verdesian describes Advance 66™ as containing chelated zinc, an essential micronutrient involved in enzyme systems, developmental processes and multiple aspects of crop metabolism.
Nutriphite®
Advance 66™ contains Verdesian's synthesised potassium phosphite, marketed within its Nutriphite® technology platform.
The manufacturer links this technology with nitrate reductase, cis-zeatin and root-development responses.
Nitrate reductase and cis-zeatin
Verdesian states that studies at Nottingham and Kiel Universities investigated the mode of action of potassium phosphite.
According to the manufacturer, potassium phosphite significantly increased production of the enzyme nitrate reductase and the hormone cis-zeatin.
Verdesian connects these biochemical responses with increased root mass and improved nutrient-use efficiency.
30% increase in cereal root mass
This figure is manufacturer-reported and should not be interpreted as a guaranteed 30% response under every field condition.
Why nitrate reductase matters
Nitrate reductase is one of the central enzymes controlling nitrate assimilation in plants.
It catalyses the first major reduction step that converts absorbed nitrate into nitrite.
Nitrite is subsequently reduced further before nitrogen can be incorporated into amino acids and proteins.
From nitrate to plant protein
Better utilisation does not create nitrogen
Verdesian states that nitrate reductase has a decisive influence on the availability and utilisation of nitrogen compounds within the plant.
Increasing the efficiency of nitrogen metabolism can help a crop make better use of nitrogen already acquired.
It does not generate new nitrogen atoms or remove the crop's fundamental nitrogen requirement.
No automatic nitrogen-rate reduction
Nitrogen rates should remain based on crop demand, soil supply, expected mineralisation, previous crop, irrigation, yield potential and locally validated recommendations.
Cis-zeatin and cytokinin biology
Cis-zeatin is a naturally occurring cytokinin-type plant hormone.
Cytokinins participate in plant-development signalling and can influence cell division, nutrient signalling, shoot-root communication and source-sink relationships.
Verdesian includes increased cis-zeatin within the described potassium-phosphite mode-of-action research.
Avoid overstating hormone effects
The cis-zeatin statement should remain tied to the manufacturer's mode-of-action research.
Expanding crop contact with soil and water
Verdesian links the manufacturer-reported increase in cereal root mass with greater contact between the root system and soil water.
A larger active root system can also create more opportunities for nutrient acquisition where nutrients are present in plant-accessible forms.
Root quantity should nevertheless be considered together with root depth, branching, fine roots, root hairs and physiological health.
Greater soil exploration can support
Root-stimulation technology cannot remove severe soil constraints
A larger potential root system still requires a physical and chemical environment in which roots can grow.
Severe compaction, saturation, salinity, drought or disease can override the benefit of improved root-growth potential.
Root restrictions
An essential micronutrient for plant metabolism
Advance 66™ is currently described by Verdesian as containing chelated zinc.
Zinc is required in relatively small quantities but is involved in many enzyme and regulatory processes.
Chelation can help maintain metal ions in a soluble complex within certain formulation and application environments, but exact chelating chemistry for Advance 66™ should be confirmed on the current product documentation.
Zinc contributes to
Diagnose deficiency separately from biostimulant use
Zinc deficiency can restrict crop development even where other nutrients are adequately supplied.
Symptoms vary by crop but can include shortened internodes, reduced leaf size, chlorosis or poor early growth.
Visual diagnosis alone can be misleading, so soil and tissue analysis are preferable where practical.
Advance 66™ is not automatically a complete Zn-correction programme
Where a deficiency is confirmed, compare the actual label zinc analysis and application rate with the crop's agronomic requirement.
Potassium phosphite is different from phosphate
Advance 66™ contains Verdesian's synthesised potassium phosphite technology.
Phosphite and phosphate are related phosphorus-containing compounds but are chemically different and do not have identical nutritional roles.
Maintain conventional phosphate nutrition
Crop phosphorus programmes should remain based on soil testing, crop requirement, fertiliser placement, yield target and local agronomic recommendations.
Potassium in potassium phosphite does not replace the base K programme
Potassium is essential for water regulation, stomatal function, enzyme activation and transport processes.
The potassium associated with a potassium-phosphite biostimulant should not automatically be assumed sufficient to meet field-scale potassium demand.
Continue to manage
1–2 L/ha per application
Current Verdesian Europe guidance lists a general Advance 66™ application-rate range of:
Actual crop rate, treatment timing and number of applications should still follow the current approved local label.
Do not select rate from the range arbitrarily
Current manufacturer concentration limits
≤ 2%
Current manufacturer guidance states that Advance 66™ should be applied at a final solution concentration no greater than 2% when used alone.
Manufacturer example: 2 L in 100 L water.
≤ 1%
When Advance 66™ is applied with another product at low water volume, Verdesian specifies a final concentration no greater than 1%.
Manufacturer example: 1 L in 100 L water.
The spray solution must comply with the applicable concentration limit while the total product quantity per hectare must remain within the approved Advance 66™ rate.
Understanding percentage concentration
These examples explain percentage calculations only and are not crop-specific rate recommendations.
1 L in 100 L
Approximately a 1% volume concentration.
2 L in 100 L
Approximately a 2% volume concentration.
2 L/ha in 100 L/ha water
Approximately a 2% spray concentration.
2 L/ha in 200 L/ha water
Approximately a 1% spray concentration.
Standard crop sprayers
Current Verdesian guidance states that Advance 66™ can be applied through standard crop sprayers using current best practices.
Sprayer calibration is important because the application must meet both the hectare-rate and spray-concentration requirements.
Check
Preparing Advance 66™ spray solution
Half-fill the sprayer
Begin with approximately half the required final water volume.
Start agitation
Ensure the sprayer agitation system is operating.
Add Advance 66™
Add the required label-approved product quantity.
Mix well
Allow adequate circulation before completing tank filling.
Complete filling
Add water to the required final spray volume.
Maintain agitation
Continue agitation during spraying and while standing until the tank is emptied.
Spray immediately
Verdesian instructs users to spray immediately after mixing.
Manufacturer describes broad tank-mix compatibility
Verdesian states that Advance 66™ is compatible with most agrochemical and plant-nutrition products.
This is broad manufacturer guidance rather than proof of compatibility with every formulation, water source or adjuvant.
All tank-mix partner labels remain controlling.
Add Advance 66™ last
Current manufacturer guidance instructs users to add Advance 66™ as the final product and spray immediately.
Why direct concentrate contact should be avoided
Agricultural formulations are designed to disperse or dissolve into a carrier, usually water.
Direct concentrate-to-concentrate contact can create temporary zones of extreme ionic strength, pH or ingredient concentration.
These conditions can increase the risk of precipitation, gel formation, separation or other physical incompatibility.
Dilute sequentially
Physical compatibility testing
Where labels allow a mixture but practical compatibility is uncertain, a proportional jar test using the actual spray water can help identify gross physical incompatibility before filling the sprayer.
Warning signs
Water chemistry can influence foliar mixtures
Water pH, hardness, alkalinity and dissolved salts can affect complex spray mixtures.
This is particularly relevant when Advance 66™ is combined with pesticides, micronutrients or other foliar nutrition products.
Check when appropriate
Successful foliar application is a sequence of steps
Deposition
Spray droplets must first reach the intended canopy.
Retention
Deposits need to remain on plant tissue rather than bounce, drift or run off.
Coverage
Suitable nozzle selection and carrier volume improve distribution.
Hydration
Rapid evaporation can shorten the hydrated contact period on the leaf.
Absorption
Formulation, cuticle condition and environment influence foliar uptake.
Crop response
Physiological response depends on crop stage, nutrient status and environmental conditions.
Weather influences foliar treatment performance
High temperature
Excessive heat can increase evaporation and crop stress.
Low humidity
Very dry air can shorten the period during which droplets remain hydrated.
Wind
Excess wind can reduce target deposition and increase drift.
Rain
Rain shortly after treatment may remove spray before sufficient interaction.
Severe crop stress
Severely wilted or damaged plants may respond differently from actively growing crops.
Growth stage
Canopy architecture and metabolic demand change through the season.
Nutrient-use efficiency still requires adequate nutrient supply
Nitrogen
Required for amino acids, proteins, enzymes, chlorophyll and new tissue.
Phosphorus
Required for ATP, membranes, genetic material and root development.
Potassium
Supports water relations, transport and enzyme activation.
Sulphur
Required for sulphur-containing amino acids and interacts closely with nitrogen metabolism.
Magnesium
Central to chlorophyll and many enzymatic processes.
Micronutrients
Zinc and other micronutrients perform specialised catalytic and structural functions.
Use soil and tissue data to understand the limiting factor
Advance 66™ is positioned around nutrient-use efficiency, but efficiency technology cannot compensate for an unidentified severe nutrient deficiency.
Soil testing provides information about nutrient supply and root-zone chemistry, while tissue analysis provides information on nutrients actually present in the crop.
Include
Pair biochemical efficiency with sound nitrogen agronomy
Advance 66™ is positioned around nitrogen utilisation rather than nitrogen loss prevention in the fertiliser itself.
This distinction matters: plant metabolic efficiency and fertiliser loss protection address different stages of the nitrogen pathway.
Manage
Strong establishment depends on coordinated root and shoot growth
Verdesian lists improved establishment among Advance 66™ benefits.
Early crop development establishes the root architecture and photosynthetic canopy that support later nutrient acquisition and yield formation.
Core agronomy
Manufacturer positioning includes growth, yield and quality
Verdesian states that greater nutrient uptake and nitrogen utilisation contribute to improved establishment, growth, yield and quality.
These are product-performance objectives rather than guaranteed outcomes for every field.
The complete production system
Measure the response under your own crop conditions
Root mass
Carefully excavate representative plants and compare root-system size and architecture.
Tissue nitrogen
Crop-stage-appropriate analysis can provide context on nitrogen status.
Tissue zinc
Helps determine whether zinc status differs between treatments.
Canopy growth
Measure biomass, leaf area, plant height or other relevant metrics.
Yield
Use properly designed treated and untreated comparisons.
Quality
Evaluate crop-specific market traits where appropriate.
Separate treatment response from normal field variability
Soil variability, drainage, fertility history and topography can create yield differences larger than the expected product response.
Replicated or well-matched strips provide stronger evidence than a single treated area compared with a distant untreated block.
Trial information
Advance 66™ fits inside a complete nutrient-management system
Biostimulant and foliar-nutrition technologies are most useful when essential nutrient supply is already managed according to crop demand.
Right source · rate · time · place
10 litres
The current Verdesian Europe product page lists Advance 66™ in a 10 L pack.
Depending on label rate
Arithmetic illustration only. Actual rate and treated area must follow the current crop-specific local label.
Advance 66™ is currently listed in Verdesian Europe resources
Advance 66™ appears in the current European product portfolio and Labels & SDS library.
This confirms current manufacturer documentation but not identical commercial availability or registration across all markets.
Confirm locally
Maintain product quality from storage to application
Original container
Maintain manufacturer labelling and lot traceability.
Follow label storage conditions
Use the current label and SDS for storage-temperature requirements.
Prevent contamination
Use clean pumps, measuring vessels and transfer equipment.
Use suitable PPE
Follow the current SDS and local workplace requirements.
Manage spills
Follow SDS and applicable environmental procedures.
Keep records
Record lot, rate, field, crop, tank mix and application date.
Avoid common Advance 66™ programme mistakes
Calling phosphite phosphate
Phosphite does not automatically replace conventional phosphate nutrition.
Using the 30% root figure as a guarantee
It is a manufacturer-reported cereal study response.
Automatically reducing nitrogen
Better nitrogen utilisation does not create an automatic N credit.
Assuming all zinc deficiencies are corrected
Compare actual zinc supplied with diagnosed crop requirement.
Confusing hectare rate and spray concentration
Both the L/ha rate and percentage concentration must be correct.
Exceeding 2% alone
Current manufacturer guidance specifies ≤2% when used alone.
Exceeding 1% in low-volume mixtures
Current guidance specifies ≤1% with another product at low water volume.
Adding Advance 66™ too early
Current manufacturer guidance says to add it last.
Allowing concentrates to contact directly
Dilute products through the water carrier rather than mixing concentrates.
Stopping agitation
Continue agitation during spraying and while standing until empty.
Storing mixed spray
Current manufacturer guidance directs users to spray immediately.
Assuming universal EMEA registration
Verify the current local Advance 66™ label before use or sale.
Information that helps us evaluate an Advance 66™ programme
Country
Determines current registration, crop use and label.
Crop
Include crop species, variety and production system.
Growth stage
Helps align foliar application with crop physiology.
Advance 66™ rate
Provide the local label-approved rate being considered.
Water volume
Required to verify final spray concentration.
Tank-mix partners
List crop-protection products, nutrients and adjuvants.
Nitrogen programme
Include source, seasonal rate and application timings.
Phosphorus programme
Confirms conventional phosphate nutrition is being maintained.
Zinc status
Include soil or tissue Zn data where available.
Soil pH
Important context for nutrient availability.
Water quality
Include pH and hardness where known.
Crop area
Supports commercial volume and logistics planning.
Advance 66™ product profile
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View Product →Build a crop-specific Advance 66™ foliar programme
Tell us your country, crop, growth stage, local Advance 66™ rate, spray-water volume, water quality, tank-mix partners, nitrogen and phosphorus programmes, zinc status and crop area. Atlas Crop Technologies can help evaluate rate, spray concentration, compatibility and practical programme integration.
Frequently Asked Questions
Manufacturer-specific statements are identified where relevant. General explanations provide agronomic context. Always follow the current approved local Advance 66™ label.
Advance 66™ is a Verdesian foliar biostimulant containing chelated zinc and Nutriphite® potassium-phosphite technology.
Verdesian positions it to maximise nutrient-use efficiency, enhance root development, increase nutrient uptake and nitrogen utilisation, and support establishment, growth, yield and quality.
In Advance 66™, Verdesian identifies Nutriphite® as its synthesised potassium-phosphite technology.
Verdesian cites increased nitrate reductase and cis-zeatin in potassium-phosphite mode-of-action studies.
Nitrate reductase is a key enzyme involved in the first major reduction step of nitrate assimilation.
No. It affects metabolism of nitrate already present in the plant.
No automatic nitrogen-rate reduction should be made. Use soil supply, crop demand and locally validated recommendations.
Cis-zeatin is a naturally occurring cytokinin-type plant hormone involved in developmental and nutrient signalling.
Current Verdesian Europe information reports a 30% increase in root mass in cereals in the cited technology studies.
No. It is a manufacturer-reported study response and should not be expected identically in every crop and environment.
A larger active root system can increase contact with soil water and nutrient reserves.
No. Severe physical restriction still requires direct soil-management measures.
Yes. Verdesian describes it as containing chelated zinc.
Zinc participates in enzyme activity, protein synthesis, auxin metabolism, membrane function and several other metabolic processes.
Use the current local product label for the exact guaranteed zinc analysis. This page does not invent a universal percentage.
Not necessarily. Severe deficiency may require a zinc programme supplying a greater amount than Advance 66™ provides at its labelled rate.
No. Phosphite and phosphate are chemically different phosphorus forms.
No automatic substitution should be made. Maintain a conventional phosphate programme based on crop requirement.
Current Verdesian Europe guidance lists 1–2 L/ha per application.
Do not assume so. Follow crop- and market-specific directions on the current local label.
Current manufacturer guidance specifies no more than 2% final solution concentration.
Current guidance specifies no more than 1% final concentration.
No. The L/ha rate controls product quantity per area, while concentration controls product proportion in the spray solution.
Half-fill the sprayer, start agitation, add Advance 66™, mix, finish filling, maintain agitation and spray immediately, according to current manufacturer guidance.
Yes. Verdesian states that agitation should continue during spraying and while standing until the tank is emptied.
Yes. Current manufacturer guidance specifically instructs users to add Advance 66™ as the final product in the mixture.
Direct contact can create high local concentrations and increase physical incompatibility risk.
Verdesian states that it is compatible with most agrochemical and plant-nutrition products, but all current product labels remain controlling.
Where all labels permit a proposed mixture, a jar test can help identify gross physical incompatibility. It does not prove crop safety.
Yes. pH, hardness, alkalinity and dissolved salts can affect complex foliar mixtures.
Current Verdesian guidance states that standard crop sprayers can be used.
Current manufacturer guidance says to spray immediately after mixing.
The current European product page lists a 10 L pack.
At 1 L/ha the arithmetic is approximately 10 ha; at 2 L/ha, approximately 5 ha. Actual crop rate must follow the current label.
Yes. It appears in the current Verdesian Europe product portfolio and Labels & SDS resource.
No. Local registration, formulation, crops, claims and availability may differ by market.
No. Verdesian positions improved yield and quality among the benefits, but field response depends on the entire production system.
Use comparable treated and untreated areas and evaluate root development, nutrient status, crop growth, yield and relevant quality measurements.
Include country, crop, growth stage, local rate, spray-water volume, water quality, tank-mix partners, nitrogen and phosphorus programmes and available zinc, soil or tissue analysis.
Include company, country, target crops, treated area, expected annual requirement, season and distribution structure.
Current Verdesian Europe information describes Advance 66™ as a proven biostimulant with chelated zinc designed to maximise nutrient-use efficiency and enhance root development.
The manufacturer states that Advance 66™ increases nutrient uptake and nitrogen utilisation and links those responses with improved crop establishment, growth, yield and quality.
Advance 66™ contains Verdesian's synthesised potassium phosphite Nutriphite® technology.
Verdesian cites studies at Nottingham and Kiel Universities in its description of potassium-phosphite mode of action and states that potassium phosphite significantly increased nitrate reductase and cis-zeatin.
Current manufacturer information reports a 30% increase in root mass in cereals associated with the increased presence of the cited enzyme and hormone. This is a manufacturer-reported study response and should not be interpreted as a guaranteed 30% root increase under all crops and field conditions.
Nitrate reductase is a key enzyme in nitrate assimilation. Increased nitrate-reductase activity does not create nitrogen and does not automatically justify reducing nitrogen fertiliser rates.
Cis-zeatin is a naturally occurring cytokinin-type plant hormone. Manufacturer statements concerning cis-zeatin should remain tied to the cited mode-of-action research and should not be extrapolated into unsupported crop-specific hormonal claims.
Advance 66™ contains chelated zinc. Zinc is an essential micronutrient, but exact zinc concentration and chelating chemistry should be confirmed from the current market-specific label and SDS.
The presence of zinc in Advance 66™ does not mean the product will necessarily supply enough zinc to correct every severe zinc deficiency.
Potassium phosphite and conventional phosphate fertiliser are chemically different. Advance 66™ should not automatically replace phosphate fertiliser required to meet crop phosphorus demand.
Likewise, potassium contained in potassium phosphite should not be assumed to replace the crop's conventional potassium fertiliser programme.
Current Verdesian Europe guidance lists Advance 66™ at 1–2 L/ha per application.
When applied alone, current manufacturer guidance specifies a final spray concentration no greater than 2%, with 2 L in 100 L water given as an example.
When applied with another product at low water volume, current manufacturer guidance specifies a final concentration no greater than 1%, with 1 L in 100 L water given as an example.
Spray concentration and product rate per hectare are different parameters; both must comply with current product directions.
Current mixing guidance states that Advance 66™ should be added to a half-filled spray tank with agitation running, mixed thoroughly, diluted to final volume, continuously agitated and sprayed immediately.
Verdesian states that Advance 66™ is compatible with most agrochemical and plant-nutrition products. Concentrated products should not come into direct contact during tank preparation and Advance 66™ should be added last.
Current manufacturer guidance lists standard crop sprayers and a 10 L pack.
Advance 66™ appears in the current Verdesian Europe Labels & SDS library. This does not establish identical registration, crop uses, formulation or availability throughout Europe, the Middle East and Africa.
Root-development responses cannot overcome severe soil compaction, waterlogging, drought, salinity, root disease or other major root-zone constraints.
Advance 66™ complements rather than replaces balanced fertility, nitrogen supply, conventional phosphate nutrition, potassium fertilisation, irrigation, soil management and crop protection.
Formulation, nutrient analysis, crops, application rates, timings, tank-mix directions, pack size, registration and permitted claims may differ by jurisdiction.
Always read and follow the current approved local Advance 66™ label and Safety Data Sheet. Consult a qualified agronomist, crop adviser or Atlas Crop Technologies representative for crop-specific rate, concentration, timing, zinc strategy, nitrogen integration, compatibility and programme guidance.